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Endocrinology 153(3):15381547 Mansoor H, L BA, Morten D, Kathleen D, G EF, R FD et al (2019a) Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

GLP-1 receptor agonists such as semaglutide and tirzepatide amplify the bodys GLP-1 response, restoring more normal signaling and offering substantial benefits for blood sugar regulation and sustainable weight loss

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This includes 39% who report currently taking a GLP-1 and 10% who have taken one but stopped

However, while these results are compelling, the authors emphasize that this is a single-subject observation and underscore the need for large-scale randomized clinical trials to validate semaglutide and similar GLP-1 RAs as primary AUD treatments