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If you want something sweet, fresh fruit, a small portion of dark chocolate, or angel food cake (which is virtually fat-free) are much safer options that will not leave you regretting the choice two hours later

Your health history, budget, insurance, and tolerance for side effects should drive the decision more than any general ranking

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Companies in large-population indications (cardiovascular, diabetes, oncology) with small-molecule pipelines face the highest IRA discount to future commercial value