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Ethical Approval The authors had permission to access and use the data from both the IQVIA LRx databases, and ethical approval was not required for secondary use of the data

11 Additionally, GLP-1R activation also induces the translocation to the nucleus of the PDX-1 transcription factor, giving GLP-1 a role in islet beta-cell survival

So far, studies show semaglutide is generally safe for long-term use

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