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semaglutide users at 12 months post-index, 0.5- and 1.0-mg formulations were the most common for both cohort 1 (38.9% and 56.0%, respectively) and cohort 2 (29.5% and 67.1%, respectively)

The truncated trial duration, MACE, and its individual components in the intervention and placebo arms were estimated

All of these unanswered questions only add to the urgency of determining who is most likely to benefit from GLP-1s. : Luliia Burmistrova / Getty

Novo Nordisk and Eli Lilly's GLP-1s offer big health benefits and are cost-effective at current US prices, but affordability remains an issue.

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