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For example, at the cellular level, primary neuronal cells from GLP-1R KO and WT mice could be cultured, and the levels of cAMP and changes in downstream phosphorylation of PKA and CREB signaling pathway after GLP-1R agonist treatment could be tested
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doi: 10.1056/NEJMoa1607141 9 ArodaVR
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Aramchol was initially produced for treatment of gallstone [59]
