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The first biosimilar formulation of a GLP-1 receptor agonist, liraglutide, has recently been marketed, at a lower acquisition cost than the original formulation, whilst oral semaglutide remains the only currently available GLP-1 receptor agonist that is administered orally

Yerba mate (Ilex paraguariensis), in turn, presents a more moderate caffeine profile, typically containing 0.3% to 1.8% of caffeine in dry weight4, and balanced levels of theobromine and theophylline