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Safety and Side Effects of Combining These Medications The combination of metformin and Trulicity is generally well-tolerated , but both medications can cause gastrointestinal side effects, which may be more pronounced when starting treatment or when used together

The product is designed as single-use pens with a number of safeguards to make it easier to take for people who aren't confident in self-injections, such as a shroud to cover the needle that administers the drug

The exact dose-response relationship in humans remains an area of active research

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doi: 10.2337/dc16-0690 57 MathieuCZinmanBHemmingssonJUWooVColmanPChristiansenEet al

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