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In contrast to other AOMs, which either suppress appetite or inhibit fat absorption [23], GLP-1RAs reduce body weight in a number of ways, decreasing appetite and hunger, and increasing satiety, resulting in reduced energy intake [2426]

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Nevertheless, compared to placebo, none of the GLP-1RAs significantly increased the risk of serious gastrointestinal complications (50)

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Mode of Action GLP-1 receptors are available in many part of the human body which allow the GLP-1 hormone to exert its functions and effects, reducing body weight, systolic blood pressure, HbA1c and lipid profile ( Figure 3 ) Figure 3: GLP-1 effect on different parts of the body

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