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The handling editor DZM declared a shared parent affiliation with the authors ND, MD, IN, PSt at the time of review

Apart from the pancreas, GLP-1R is also widely distributed in various tissues of the body including the lungs, kidneys, central nervous system, cardiovascular system, gastrointestinal tract, and skin and vagus nerves ( Glucagon like peptide-1 receptor agonists (GLP-1RAs) are emerging glucose control drugs, which are widely used in the treatment of T2MD in recent years

Other researchers in the GLP-1 field were also reluctant to go down the obesity path
Common examples include side effects, insurance coverage changes, and availability issues