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glp 1 and osa Frontiers The expanding scope of GLP-1

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DPP4 contributes to the degradation of incretin hormones, specifically glucagonlike peptide 1 (GLP1) and glucosedependent insulinotropic peptide (GIP), by cleavage of a dipeptide from their N termini

glp 1 and osa Frontiers The expanding scope of GLP-1

Tirzepatide exhibited the highest risk of gastrointestinal side effects, whereas dulaglutide and exenatide showed relatively better tolerability

glp 1 and osa Frontiers The expanding scope of GLP-1

These neurological changes also appear to extend beyond food for some people

glp 1 and osa Frontiers The expanding scope of GLP-1

Important but less common side effects include: Hypoglycaemia (low blood sugar) : particularly in patients with type 2 diabetes taking other glucose-lowering medications

glp 1 and osa Frontiers The expanding scope of GLP-1

Benefits include decreased exacerbation frequency, improved functional testing, and improved patient-reported quality of life

glp 1 and osa Frontiers The expanding scope of GLP-1

3qv and Extended Data Fig

glp 1 and osa Frontiers The expanding scope of GLP-1

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