glp 1 and osa Frontiers The expanding scope of GLP-1
Description
DPP4 contributes to the degradation of incretin hormones, specifically glucagonlike peptide 1 (GLP1) and glucosedependent insulinotropic peptide (GIP), by cleavage of a dipeptide from their N termini

Tirzepatide exhibited the highest risk of gastrointestinal side effects, whereas dulaglutide and exenatide showed relatively better tolerability

These neurological changes also appear to extend beyond food for some people

Important but less common side effects include: Hypoglycaemia (low blood sugar) : particularly in patients with type 2 diabetes taking other glucose-lowering medications

Benefits include decreased exacerbation frequency, improved functional testing, and improved patient-reported quality of life

3qv and Extended Data Fig
