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Conclusions The findings of this meta-analysis of seven RCTs (6609 participants) suggest a dose-dependent superiority of all three tirzepatide maintenance doses on glycaemic control, not only vs placebo but also vs long-acting GLP-1 RAs and basal insulin regimens

If you suspect an adverse reaction to a GLP-1 medication, report it to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

What if I want to pause or skip a month

Exercise preserves muscle mass, meaning more of the weight lost comes from fat rather than lean tissue

Supplement: Adding a metabolite of leucine known as HMB, can significantly reduce muscle breakdown and promote growth, even without exercise Supplements For GLP-1 Side Effects HMB: The Shield for Muscle Yield When it comes to preserving muscle during weight loss - especially if you're using GLP-1 medication HMB (Beta-Hydroxy Beta-Methylbutyrate) is a game-changer

This helps maintain hormonal balance, reducing the risk of excessive hormone levels and making it a safer, more natural option for many patients