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Additionally, the activities of enzymes, transporters, and cytoskeleton proteins on BBB microvessels are preferentially suppressed in these DIO animals

The addition of oligofructose as a prebiotic to the diet in ob/ob mice significantly increases plasma GLP-1, colonic L cell abundance, and colon proglucagon mRNA levels 73,74 , and GLP-2R antagonism blunts the anti-inflammatory effects of this prebiotic treatment 73

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Patients taking GLP-1 receptor agonists should be aware of both common and concerning skin manifestations that may occur during treatment

Integrative neurocircuits that control metabolism and food intake