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Description
Providers typically follow established titration schedules to allow tolerance to develop

L., Levangie, D., & Keshen, A

Notably, weight loss is not addressed during this stage, and attempts to lose weight are discouraged, as they may inadvertently trigger dysfunctional dieting behaviors
However, as millions of people started taking this drug, reports of severe side effects began circulating

A recent meta-analysis conducted on elderly T2D patients (15 studies, n = 11,679) evidenced that a combination of GLP-1RAs with SGLT2is (with an intervention period of at least six months), beyond demonstrating a positive safety profile, gave more benefits over monotherapy in terms of glycemic control, weight management, and CV protection [137]
1 Further, the United States has seen increased spend on obesity-related illnesses, 2 resulting in increased demand for weight loss solutions