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They are often used in combination with a Metformin drug

Some people also benefit from temporarily avoiding heavy or oily meals until symptoms improve

The early phase begins within minutes of eating, when nutrients in the upper gastrointestinal tract trigger neural and hormonal signals that stimulate L-cells even before food reaches the distal intestine

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The glucose-dependency of GLP-1s insulinotropic effect it only amplifies insulin secretion when blood glucose is elevated is a key pharmacological property that distinguishes GLP-1 from non-incretin insulin secretagogues in research models

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