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Marso SP, Bain SC, Consoli A, et al

(2023) published in The Lancet evaluated retatrutide dosing in subjects with type 2 diabetes

One big caveat: When paired together, GIP amplifies the effects of GLP-1, creating a synergistic effect on mobilizing fatty acids out of fat cells

Weeks 5-8 (5mg): This is where most patients begin feeling a meaningful difference

Dietary adjustments are the life-blood of management - patients should eat smaller, frequent, low-fat meals and stay hydrated [10]