semaglutide vs tirzepitide ✨ vs. Tirzepatide — What's the Difference? ✨ When it comes to medical weight loss, there's no one-size-fits-all approach — and that's where we come in. Semaglutide works by mimicking a GLP-1 medications are marketed to

As Aleem Kanji, MD , board-certified endocrinologist and obesity medicine specialist at Ethos Endocrinology, notes, perioperative management of GLP-1 medications requires coordination between your prescribing doctor and surgical team, discontinuing GLP-1 medications before elective surgery, typically 1 week for weekly injections and 1 day for daily oral formulations, to reduce aspiration risk during anesthesia

The MHRA SmPC advises maintaining adequate hydration, especially when starting treatment or increasing the dose

In the STEP clinical trials, patients on semaglutide lost an average of 15 to 17% of body weight over 68 weeks

This reduces safety risks associated with unsupervised or compounded medication sources

Semaglutide reduces liver fat

Proper medication handling is important: store pens according to product-specific instructions (typically refrigerated until first use), never share pens or needles with others, and rotate injection sites to prevent tissue changes