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These receptors are present on both neuronal cell bodies and axonal projections and are found in GABAergic and glutamatergic neurons depending on the region [71]

ONeil et al., 2018

They are widely recognized for their ability to curb appetite, support blood sugar control, and help patients lose weight more effectively than diet and exercise alone

Of these drugs, glucagon-like peptide 1 receptor (GLP-1R) agonists are more effective and have fewer side effects

For some patients, GLP-1 microdosing might work, but for others it might not be a realistic option

Synovial tissue and GLP-1R signalling Specialized cells, fibroblast-like synoviocytes and macrophage-like synoviocytes reside in the synovial membrane, composed of intimal and subintimal layers, which are responsible for notably producing hyaluronic acid and removing metabolites and matrix degradation debris, respectively [49]