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GLP-1 receptors are expressed both centrally (in the brain) and peripherally (in immune cells, the gut, and metabolic tissues)
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JAMA , 327 (6), 534
Some prefer a steadier effect, even if onset is slower
GIP (glucose-dependent insulinotropic polypeptide): This is the second pathway targeted by tirzepatide (Zepbound, Mounjaro)
