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In the context of prolonged systemic administration, NMDA receptor antagonists, such as memantine and MK-801 (also known as dizocilpine), induce anorexia and weight loss in rodents 9,10,11

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GLP-1 medicines are created for people with diagnosed medical requirements, that includes diabetes or clinically significant weight-related health challenges, and should not be utilized purely for appearance-driven weight reduction

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When treatment ends, the physiological effects reverse

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants with Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (Together Amplify-Psa)