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Prior to treatment, medium was replaced and supplemented with 0.1% BSA, and cells were incubated at 37C overnight

These mice have major kidney abnormalities including enhanced oxidative stress, enhanced activity of the inflammasome, and fibrosis, all features of CKD

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Each injection session is quick and easy, typically administered at a healthcare facility, though some patients may be trained to self-administer the injection at home after their first few sessions

The carbohydrate reduction on keto, combined with the blood sugar lowering effects of both medications, can drop glucose into dangerously low territory