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Theyre supported by years of data, regulated by the FDA, and often covered by insurance

There are several classes of diabetes medications, including incretin mimetics (like Ozempic), sulfonylureas, biguanides (including metformin, the most commonly used drug to treat type 2 diabetes), DPP-4 inhibitors, SGLT2 inhibitors, and insulin, among others

Two studies on exenatide 162,166 and one on liraglutide 162 showed no effect of these GLP-1RAs on depression-like behavior

In people with overweight/obesity and non-diabetic CKD who were included in the SMART study, 2.4 mg semaglutide once weekly versus placebo reduced UACR by 52% at 24 weeks of treatment (87)

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