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Razia Hashmi, chief medical officer at the Blue Cross Blue Shield Association, put it bluntly: "The current insurance construct was not designed to handle this kind of demand." She was right

Mol Cell Biochem

584 In a large, randomized, controlled trial, 21,442 U.S
In the TRANSCEND-T2D-1 trial, which was simultaneously published in The Lancet , HbA1c declined by 1.9 percentage points at 40 weeks for adults with type 2 diabetes with the two highest doses of the drug

New England Journal of Medicine 2011;364:2187-2198
The most plausible rationale for the discrepancy between preclinical/epidemiological success and clinical failure lies in the fundamental distinction between prevention and treatment
