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For weight management, NICE (TA875) recommends semaglutide 2.4 mg (Wegovy) for adults with a BMI of 35 kg/m or greater (or 32.5 kg/m or greater for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds) who have at least one weight-related comorbidity

doi: 10.1111/j.1464-5491.2010.03020.x

The new approval for Retevmo, which was previously authorized to treat patients 12 and older with RET-positive thyroid cancers, is based on a single-arm study that showed an overall response rate of 48%, with a median duration of response not reached after 12 months of follow-up

Clinical trials have demonstrated that significant improvements in HbA1c (a measure of average blood glucose over three months) occur over the first 3 to 6 months of therapy

There is limited experience with liraglutide injection in patients with end stage renal disease

I have seen them being advertised and sold on TikTok- which is worrying