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To extensively evaluate the roles of intestinal NAMPT-mediated NAD + biosynthesis in intestinal homeostasis and glucose metabolism, an intestinal epithelial cell-specific NKO mouse model (INKO) was established [31]

Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice

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TC10 also reduced blood glucose in glucose tolerance testing

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