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The most commonly reported adverse events were gastrointestinal disorders and hypoglycemia in patients with type 2 diabetes concurrently using sulfonylureas, metformin, and/or SGLT-2 inhibitors

doi: 10.3390/nu10030297 120 BabbsRKSunXFelstedJChouinard-DecorteFVeldhuizenMGSmallDM

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They probably have other psychological issues perhaps, or they stayed away from fitness and sports because they were never good at them or they were embarrassed to do it, so they don't have the skill set and the liking of being physically active