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Finally, gastrointestinal side effects such as nausea, vomiting, and diarrhea can lead to dehydration and challenged sleep, both of which contribute to exhaustion

Some users report changes in energy or exercise tolerance within the first few weeks, but responses vary

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Furthermore, while initial clinical studies focused on patients with T2D, the kidney-protective role of GLP-1 receptor agonists has now been extended to individuals without T2D