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Semaglutide strengthens this signal

Dipeptidyl peptidase-4 inhibitors and risk of heart failure in type 2 diabetes: systematic review and meta-analysis of randomised and observational studies

AprilJune 2016

The STEP-HFpEF-DM trial confirmed the benefits of once-weekly semaglutide also in obese patients affected by type 2 diabetes

Although regulators reviewed data from more than 90 clinical trials involving over 100,000 patients and found no statistically significant increase in suicidal thoughts compared to placebo, critics argue the decision comes too soon
