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As a result, the half-life was extended to 1516 days (compared to the one-week duration of analogs like semaglutide or tirzepatide) while maintaining equivalent potency, opening the door for once-monthly instead of weekly administration

[DOI] [PubMed] [Google Scholar] 141.Watson C.J., Whitledge J.D., Siani A.M., Burns M.M

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