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doi: 10.1001/jama.2021.1831 [DOI] [PMC free article] [PubMed] [Google Scholar] 6.Wilding JPH, Batterham RL, Calanna S, et al

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Conversely, in chronic treated patients the effects on volume changes are slightly reduced because a new steady state is reached, due to a counter-regulatory effect, resulting in a lower total body sodium concentration and blood volume (53)

[cited 2022 Oct 15]

GLP-1 weight loss medications are administered as a simple, once-weekly subcutaneous injection

And the bar keeps rising