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Drug choice may matter less than dose and duration

Storage and handling considerations Both medications require proper storage to maintain potency and safety

This non-peptide mechanism, elucidated through cryo-electron microscopy and published in the Proceedings of the National Academy of Sciences in 2020, overturned decades of pharmacological dogma that class B GPCRs could only be meaningfully activated by peptide ligands

N Engl J Med 389(12):10691084

They may have a preference for one version or the other

The rapid onset of the Adderall IR formulation can be quick and intense, but it doesn't last as long as the extended-release formulation
