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33 Although decreases in gastric emptying via GLP-1RAs help prevent overnutrition by decreasing nutrient absorption, there is concern that patients could be at risk of nutrient deficiencies driven by malabsorption from delayed gastric emptying

Then, Novo Nordisk worked on a new generation GLP-1 RA, semaglutide, and commercialized it successfully

Dickson et al., 2012)

Significant fluctuations in blood sugar levels can damage blood vessels in the retina if not well-controlled, potentially leading to serious vision problems and even blindness if left untreated

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