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Regulatory reality: Tesamorelins approved-drug status (EGRIFTA) brings a real prescribing label with IGF-1 and glucose monitoring requirements and clear contraindications which is why those safety rules carry over to the research framing here

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These cardiovascular advantages have made GLP-1 medications a preferred choice for type 2 diabetes patients with established cardiovascular disease
Those were originally intended for use with diabetes and function by stimulating the release of insulin from the pancreas, which lowers blood sugar, as well as slowing the digestion of food in order to reduce appetite, which promotes weight loss

doi: 10.1016/j.ijbiomac.2021.10.188 27 DepommierC.EverardA.DruartC.PlovierH.Van HulM.Vieira-SilvaS.et al

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