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GI side effects broadly in line with injectables

GLP3-R is a triple agonist targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

Anyone with type 1 diabetes, type 2 diabetes on insulin or sulfonylureas, history of pancreatitis, personal or family history of medullary thyroid cancer, or multiple endocrine neoplasia syndrome type 2 should only use Retatrutide under direct medical supervision with adjusted medication protocols

Swedish registry data indicated a 77% reduction in mortality risk in the BSx subgroup with preoperative HF versus the nonsurgical control group [172]

Nutrition, resistance training, sleep, alcohol intake, and other medications can all affect results