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Additionally, dehydration from gastrointestinal side effects may increase the risk of acute kidney injury, and gallbladder disease has been reported with incretin-based therapies

Diab H, Fuquay T, Datta P, Bickel U, Thompson J, Krutsch K

2.2 SURMOUNT study program TZP treatment induced a significant BW reduction in diabetic patients who were obese or overweight

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Medical nutrition therapy interventions provided by dietitians for adult overweight and obesity management: an academy of nutrition and dietetics evidencebased practice guideline