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However, in PD pathogenesis, oligomerisation of S downregulates Sirt3 (Park et al., 2020), resulting in decreased phosphorylation of AMPK and increased phosphorylation of Drp1, impairing mitochondrial respiration, and leading to apoptosis

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[4] Coverage requires BMI 40 AND participation in weight loss program (diet, exercise, behavior therapy) Coverage for Type 2 diabetes remains unchanged Anthem Blue Cross California policies may differ BCBS Massachusetts Starting January 1, 2026, BCBS MA standard plans will exclude GLP-1s including Zepbound, Wegovy, and Saxenda for weight management
