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Why the caveats: Most human data is observational, not randomized controlled trials designed to prove prevents dementia. So far, we cannot definitively say GLP-1 RAs prevent Alzheimers

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Aims/hypothesis A protective role of sodiumglucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP1-ra) in the development of diabetic retinopathy and diabetic macular oedema has been described in some recent studies, which may extend beyond glycaemic control