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This review adopts a structured narrative framework designed to integrate mechanistic, translational, and clinical insights across heterogeneous study types

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Whilst GLP-1 receptor agonists have demonstrated benefits in metabolic health and cardiovascular outcomes in specific populations, their role in conditions beyond diabetes and obesitysuch as lymphoedemaremains an area of emerging interest rather than established clinical practice

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Patients also saw significant improvement in central nervous system diseasefree survival, according to an exploratory analysis

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