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New research from Sweden has found that GLP-1 agonist drugs used to treat diabetes and obesity are unlikely to increase thyroid cancer risk, as some previous studies had suggested.

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Improving the plumbing does not repair the degenerating circuitry. These images show thehuman hippocampus, a memory-critical region, in Alzheimers disease: H&E (top left):overall structural collapse, neuronal loss, inflammation

Our results reveal the existence of residue networks crucial for unimolecular agonist-mediated receptor activation and their distinct signaling patterns, which might be useful to the rational design of biased drug leads.

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