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The mortality risk associated with T2DM is only secondary to an increase in an individuals risk of acquiring other disease states that are both vascular and nonvascular in origin [1]

A hormone is a chemical messenger that travels through the blood to reach different organs and tissues

In RCT studies on T1D, at the initiation of GLP-1RA therapy, bolus insulin was reduced ~25-33% and basal insulin ~10-25% (5661) as observed in Table 1

Vomiting : Often accompanies nausea and can lead to dehydration if persistent

Data from the large cardiovascular safety studies with DPP-4 inhibitors (see section below) did not show a respective signal

Notice the continued reference to both overweight and obesity, since referring only to obesity may contribute to overlooking the risks and therapeutic opportunities associated with overweight