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For instance, Kaiser Permanente plans to revise its coverage criteria starting January 1, 2025, leading to inquiries about whether Kaiser covers weight loss drugs, as it will exclude coverage for GLP-1 medications when prescribed exclusively for reducing body mass in patients with a BMI under 40

The decision tree is not binary or permanent

For instance, 15.8% of people taking a 0.5 mg injection experienced nausea, compared to 20.3% of people taking a 1.0 mg injection in clinical trials

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Studies in the New England Journal of Medicine confirm that continuous GLP-1 therapy maintains weight loss, while discontinuation leads to predictable regain regardless of diet adherence