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Distinguishing features that suggest inflammatory bowel conditions rather than expected Wegovy side effects include: Blood in stools (though some forms of colitis, such as microscopic colitis, typically present with persistent non-bloody diarrhoea) Persistent nocturnal diarrhoea disrupting sleep Severe, unremitting abdominal pain Unintentional weight loss beyond expected therapeutic effects Fever accompanying gastrointestinal symptoms Elevated inflammatory markers (CRP, ESR) or faecal calprotectin Progressive worsening rather than improvement over time Recognising these distinctions enables appropriate clinical decision-making regarding symptom management versus further investigation

J., Boyles, J

However, Wegovy works best when combined with a reduced-calorie diet and increased physical activity

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These two possible contributing causes need additional investigation

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