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Long-term NMDAR antagonism correlates weight loss with less eating

Its a little-known consequence of the obesity drug boom, according to doctors who caution eager patients not to expect one-size-fits-all results

This effect appears to explain the carbohydrate stimulated ileal brake where plasma GLP-1 increases without a change in PYY (64)

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Evidence for Cardiovascular Safety The DPP-4 inhibitors have not demonstrated any sustained or clinically significant reduction in other cardiovascular risk factors, such as blood pressure or lipids

Using degraded drops means you are taking a lower effective dose than intended, which explains sudden loss of appetite control or weight loss plateaus