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The researchers wanted to investigate whether engaging additional metabolic signaling pathways would alter the animals physiological response

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Apolipoprotein E (ApoE), a protein interacting with cell surface receptors to facilitate the uptake of lipoproteins [72], is postulated to hinder the clearance of soluble A from the brain by competing with soluble A for LRP1dependent cellular uptake into astrocytes [73]

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Liraglutide and insulin have contrary effects on adipogenesis of human adipose-derived stem cells via wnt pathway

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