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GLP-1RAs also downregulate the expression of MMPs and tissue inhibitors of MPs (TIMPs) for anti-inflammation [110]

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GLP-1 receptor agonists have revealed notable weight loss outcomes, leading to their increasing use beyond diabetes care

The same finding had been reported by a prior larger meta-analysis (6,914 patients with overweight or obesity and T2DM) over 8 studies 184,185,189,190,191,192,193,194 , but only when the largest study that also included non-diabetic participants 193 was excluded in a sensitivity analysis 195
My network is a small sample size, but I see its benefits and no real known negative effects yet