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In 12 month old APP/PS1 mice, a transgenic mouse model for AD [284,1067], treatment with [D-Ala 2 ]GIP protects from impairment of learning and memory, and these effects are paralleled by reduced synaptic loss, preservation of synaptic plasticity, decreased amyloid plaque formation and amelioration of inflammation, oxidative stress, and DNA damage [1068,1069]

By helping clients manage hunger signals more effectively, GLP-1 medications support long-term adherence to healthy eating and exercise routines

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