how much is glp 1 out of pocket cost for Study finds GLP-1 costs outweigh benefits Poll: 1 in 8 Adults
Description
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GLP-1 Side Effects While GLP-1 drug therapy is generally safe, some patients may experience mild side effects such as: Nausea Vomiting Diarrhea Constipation Headache Fatigue Most side effects lessen with time as the body adjusts

Emerging research suggests yes
My rebuttal to that concern comes from the SELECT trial testing Wegovy in patients with heart disease

Postmarket Drug Safety Information

Incretin action may also be reduced during hyperglycemia and in some individuals with diabetes, prediabetes and insulin resistance [571]