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Subjects treated with a GLP-1RA had a greater absolute number of BC occurrences in the Randomized controlled trial of the Liraglutide Clinical Development Program [154]

At the 10 mg/kg dose of GSBR-1290, the average food intake from day one to day six was only 59% of that in the Liraglutide group

Scientists later identified that hormone as glucagon-like peptide 1GLP-1

While semaglutide has proven effective in managing blood sugar and promoting weight loss, its effects on certain rare cancer types warrant caution, the researchers note in their in-press article in the journal Surgery

For example, Corxcel (Exheliums spinoff) is developing an oral GLP-1 pill

Additionally, further research is needed to explore the broader therapeutic potential of these agents in managing comorbidities such as cardiovascular disease, PCOS, CKD, MASH, and osteoarthritis