how do glp 1 drugs work for weight loss GLP-1 Drugs: Semaglutide & Tirzepatide Redefine Obesity Care What are GLP-1s? | Mendinground

Discussion While the overall number of GLP-1 RA exposures increased during the study period, outcomes were largely benign, with the most common being no effect

GLP-1 receptor agonist medications are typically used to treat type 2 diabetes and obesity, although their use is expanding to other health conditions

Some brain imaging studies have demonstrated that depressed patients show neuronal atrophy and decreased volume of the cortex and limbic lobe regions, including the PFC and hippocampus

10.1186/s10194-024-01821-3

Also, as an anabolic hormone, insulin promotes fat storage, and chronic hyperinsulinemia, commonly observed in T2DM, further stimulates lipogenesis while suppressing lipolysis, thereby counteracting BW reduction

GLP-1-based therapies led to favorable changes in body composition, with significant reductions in VAT and FBM, particularly during the first six months