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Familial hypercholesterolemia: Identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol

Clinical trial data shows weight regain typically begins within 6 to 12 months of complete discontinuation, supporting ongoing maintenance rather than stopping entirely

Original research based on a very large cohort of people living with PWS, aiming to investigate the genotype-phenotype correlation, would be appreciated as they would shed new light on these features, supporting clinicians in optimizing follow-up

They are critical for meeting the unprecedented demand for prefilled syringes and autoinjectors, which has outpaced market preparation and created a significant capacity shortfall

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The challenge is the human behavior