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If the short-term approach has already failed you, repeating it is unlikely to produce a different outcome

Saxagliptin but not sitagliptin inhibits CaMKII and PKC via DPP9 inhibition in cardiomyocytes

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19 In regard to CKD, these clinical trials have also shown positive effects in the composite renal outcomes

But in addition to the oral compound, the branded medications, the personalized GLP-1 doses, which augment the commercially available dosages for patients that need it as well as off-patent GLP-1s like liraglutide, I think we believe the combination of that portfolio, allows customers and providers a really robust range of offerings that we think is very durable